People with cancer can’t wait. Let’s go.

The full potential of targeted oncology is waiting to be unlocked. That’s why we relentlessly pursue every possibility to create new cancer breakthroughs and power our approach with people who think hard, care hard and act with urgency.

At SpringWorks, we bring tenacity to work every day because patients need answers now.

Recent News

SpringWorks Therapeutics Initiates Rolling Submission of New Drug Application to the FDA for Mirdametinib for the Treatment of Children and Adults with NF1-PN
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SpringWorks Therapeutics Announces European Medicines Agency Validation for Marketing Authorization Application of Nirogacestat for the Treatment of Adults with Desmoid Tumors
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SpringWorks Therapeutics Reports Fourth Quarter and Full Year 2023 Financial Results and Highlights Recent Business Updates
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Lets go

Let’s get novel for rare oncology

Our late-stage rare oncology programs have the potential to be best-in-class treatments for patients with devastating diseases.

Let’s dig into BCMA combinations
in multiple myeloma

Our gamma secretase inhibitor, nirogacestat, is being evaluated as part of several B-cell maturation agent (BCMA) combination therapy regimens in collaboration with industry and academia.

Let’s take on biomarker-defined metastatic solid tumors

We are using a precision oncology approach to evaluate investigational medicines for highly-prevalent, biomarker-defined metastatic cancers in monotherapy and combination therapy studies. If successful, our programs could potentially address more than one-third of solid tumor patients.

People with devastating
diseases need more champions.

Let’s make a difference.

We understand the physical and emotional toll of living with a severe rare disease or a devastating cancer, which is why we are committed to developing new treatments for people dealing with them. Helping people live longer, healthier lives is core to our mission and central to our work.

Our values drive us

Care Hard

We take caring very seriously. We care about our patients deeply, intensely, and relentlessly. Every day, we care for patients by working harder to develop solutions others haven’t.

Ambition Without Ego

We exist to ignite the power of promising science to unleash new possibilities for patients. To make this audacious ambition a reality, we must not let personal pride, empty rhetoric, or ego get in the way.

Think Deeply, Act Quickly

Our team is measured, comprehensive, and thoughtful about every move we make, but we’re also driven by a sense of urgency because we know that patients are waiting. We delicately and expertly balance thinking and acting while always upholding our commitment to the highest standards of ethics and integrity.

Good Enough is Never Enough

“Good enough” is never enough for the patients and families counting on us. That’s why we constantly push ourselves to become smarter, better, and faster in pursuit of our ambition.

In It Together

We’re a team, first and foremost. Each and every SpringWorker is all in with their coworkers, partners, and patients. We do our best work when we all get together, hurling jokes and big ideas, and collectively making it happen.

One of the challenges with desmoid tumors is that they are extraordinarily aggressive locally and can grow at a relatively rapid pace. Over the course of two years, my tumor grew from the size of a small green pea to the size of a football, and it was located in my calf. My desmoid tumors completely changed my life and led to my leg being amputated.
Dana, Desmoid Tumor Patient
Dana has been living with desmoid tumors for more than 20 years. Watch her story.

Join the Pursuit

We give it our all every day because we believe targeted oncology is the best way to change the outlook for people with cancer. The answers are waiting. Let’s go find them together.